Article
MAOA-VNTR polymorphism modulates context-dependent dopamine release and aggressive behavior in males.
NeuroImage - 15 Jan 2016
Schlüter Thorben, Winz Oliver, Henkel Karsten, Eggermann Thomas, Mohammadkhani-Shali Siamak, Dietrich Claudia, Heinzel Alexander, Decker Michel, Cumming Paul, Zerres Klaus, Piel Markus, Mottaghy Felix M, Vernaleken Ingo
Abstract excerpt
A recent [(18)F]FDOPA-PET study reports negative correlations between dopamine synthesis rates and aggressive behavior. Since dopamine is among the substrates for monoamine oxidase A (MAOA), this investigation examines whether functional allelic variants of the MAOA tandem repeat (VNTR) promotor polymorphism, which is known to modulate aggressive behavior, influences dopamine release and aggression in response to...
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