Article
Diagnosis of a Family with the Novel -α(21.9) Thalassemia Deletion.
Hemoglobin - 1 Jan 2015
Long Ju, Pang Wanrong, Sun Lei, Lao Kegan, Weng Xunjin, Ye Xuehe, Wu Suping, Song Chuanlu, Wei Xiaoying, Yan Shanhuo
Abstract excerpt
The Qinzhou α-thalassemia (α-thal) or -α(21.9) deletion was first described at the Qinzhou Maternal and Child Health Care Hospital, Qinzhou, Guangxi, People's Republic of China (PRC) in 2013. The molecular biological mechanism by which this allele leads to α-thal involves the deletion of a 21.9 kb DNA fragment of the α-globin gene cluster (NG_000006.1), designated as -α(21.9). During routine screening, a new...
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