Article
Association of polymorphisms in PRKCI gene and risk of prostate cancer in a sample of Iranian Population.
Cellular and molecular biology (Noisy-le-Grand, France) - 16 Oct 2015
Hashemi M, Shahkar G, Simforoosh N, Basiri A, Ziaee S A M, Narouie B, Taheri M
Abstract excerpt
The atypical protein kinase C iota (aPKCι) is an oncoprotein encoded by the PRKCI gene. It has been reported to play multifunctional roles in cellular maintenance, cell proliferation, survival, differentiation and apoptosis. In the present study we aimed to assess the impact of PRKCI rs546950 C>T and rs4955720 C>A polymorphisms on prostate cancer (PCa) risk in a sample of Iranian population. This case-control...
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