Article
Effects of brain derived neurotrophic factor Val66Met polymorphism in patients with cervical spondylotic myelopathy.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Feb 2016
Abode-Iyamah Kingsley O, Stoner Kirsten E, Grossbach Andrew J, Viljoen Stephanus V, McHenry Colleen L, Petrie Michael A, Dahdaleh Nader S, Grosland Nicole M, Shields Richard K, Howard Matthew A
Abstract excerpt
Cervical spondylotic myelopathy (CSM) is the leading cause of spinal cord related disability in the elderly. It results from degenerative narrowing of the spinal canal, which causes spinal cord compression. This leads to gait instability, loss of dexterity, weakness, numbness and urinary dysfunction. There has been indirect data that implicates a genetic component to CSM. Such a finding may contribute to the...
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