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Article

A nonsense mutation in B3GALNT2 is concordant with hydrocephalus in Friesian horses.

BMC genomics - 9 Oct 2015

Ducro Bart J, Schurink Anouk, Bastiaansen John W M, Boegheim Iris J M, van Steenbeek Frank G, Vos-Loohuis Manon, Nijman Isaac J, Monroe Glen R, Hellinga Ids, Dibbits Bert W, Back Willem, Leegwater Peter A J

Abstract excerpt

BACKGROUND: Hydrocephalus in Friesian horses is a developmental disorder that often results in stillbirth of affected foals and dystocia in dams. The occurrence is probably related to a founder effect and inbreeding in the population. The aim of our study was to find genomic associations, to investigate the mode of inheritance, to allow a DNA test for hydrocephalus in Friesian horses to be developed. In case of a...

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Identifiers

PMID: 26452345
DOI: 10.1186/s12864-015-1936-z
PMCID: PMC4600337

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