Article
LINE-1 Methylation Patterns as a Predictor of Postmolar Gestational Trophoblastic Neoplasia.
BioMed research international - 1 Jan 2015
Lertkhachonsuk Ruangsak, Paiwattananupant Krissada, Tantbirojn Patou, Rattanatanyong Prakasit, Mutirangura Apiwat
Abstract excerpt
OBJECTIVE: To study the potential of long interspersed element-1 (LINE-1) methylation change in the prediction of postmolar gestational trophoblastic neoplasia (GTN). METHODS: The LINE-1 methylation pattern from first trimester placenta, hydatidiform mole, and malignant trophoblast specimens were compared. Then, hydatidiform mole patients from 11999 to 2010 were classified into the following 2 groups: a remission...
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