Article
Treatment of dystrophic epidermolysis bullosa with bone marrow non-hematopoeitic stem cells: a randomized controlled trial.
Dermatologic therapy - 1 Jan 2000
El-Darouti Mohammad, Fawzy Marwa, Amin Iman, Abdel Hay Rania, Hegazy Rehab, Gabr Hala, El Maadawi Zeinab
Abstract excerpt
Patients with dystrophic epidermolysis bullosa (DEB) have mutations in type VII collagen gene. Type VII collagen is synthesized by keratinocytes and fibroblasts. Based on the ability of bone marrow non-hematopoeitic stem cells (NHBMSC) to develop into fibroblasts, we decided to investigate the use of NHBMSC in the treatment of recessive DEB (RDEB). This study included fourteen patients with RDEB; the first seven...
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