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Article

Oxidative status in treatment-naïve essential thrombocythemia: a pilot study in a single center.

Hematological oncology - 1 Sept 2017

Iurlo Alessandra, De Giuseppe Rachele, Sciumè Mariarita, Cattaneo Daniele, Fermo Elisa, De Vita Claudia, Consonni Dario, Maiavacca Rita, Bamonti Fabrizia, Gianelli Umberto, Cortelezzi Agostino

Abstract excerpt

Oxidative stress (OS), due to pro-oxidant species [reactive oxygen species (ROS)] excess not counterbalanced by endogenous antioxidant molecules [e.g., reduced glutathione (GSH)], is involved in the pathogenesis of human cancers, but few data are available on essential thrombocythemia (ET). This study aims to investigate OS in ET off-therapy patients. Thirty ET treatment-naïve patients were compared with 26...

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PMID: 26437571
DOI: 10.1002/hon.2264

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JAK2

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