Article
CYP2D6 Genotype and Risk of Recurrence in Tamoxifen Treated Breast Cancer Patients.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Yazdi Mohammad Forat, Rafieian Shiva, Gholi-Nataj Mohsen, Sheikhha Mohammad Hasan, Nazari Tahereh, Neamatzadeh Hossein
Abstract excerpt
BACKGROUND: Despite consistent pharmacogenetic effects of CYP2D6 on tamoxifen exposure, there is considerable controversy regarding the validity of CYP2D6 as a predictor of tamoxifen outcome. Understanding the current state of evidence in this area and its limitations is important for the care of patients who require endocrine therapy for breast cancer. MATERIALS AND METHODS: A total of 101 patients with breast...
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