Molecular basis of familial hypercholesterolemia.

Article

Molecular basis of familial hypercholesterolemia.

Arteriosclerosis (Dallas, Tex.) - 1 Jan 2000

Russell D W, Esser V, Hobbs H H

Abstract excerpt

Familial hypercholesterolemia (FH) is a genetic disease characterized by an elevated level of low density lipoprotein (LDL), xanthomas, and an increased frequency of heart attacks. One of the first descriptions of this disease was reported some 50 years ago by the Norwegian physician, Carl Müller...

Topics

Genes
Humans
Hyperlipoproteinemia Type II
Mutation
RNA, Messenger
Receptors, LDL
Structure-Activity Relationship

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.