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Article

ORF8-Related Genetic Evidence for Chinese Horseshoe Bats as the Source of Human Severe Acute Respiratory Syndrome Coronavirus.

The Journal of infectious diseases - 15 Feb 2016

Wu Zhiqiang, Yang Li, Ren Xianwen, Zhang Junpeng, Yang Fan, Zhang Shuyi, Jin Qi

Abstract excerpt

Several lineage B betacoronaviruses termed severe acute respiratory syndrome (SARS)-like CoVs (SL-CoVs) were identified from Rhinolophus bats in China. These viruses are characterized by a set of unique accessory open reading frames (ORFs) that are located between the M and N genes. Among unique accessory ORFs, ORF8 is most hypervariable. In this study, the ORF8s of all SL-CoVs were classified into 3 types, and,...

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Identifiers

PMID: 26433221
DOI: 10.1093/infdis/jiv476
PMCID: PMC7107392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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