Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chlamydial plasmid-encoded virulence factor Pgp3 neutralizes the antichlamydial activity of human cathelicidin LL-37.

Infection and immunity - 1 Dec 2015

Hou Shuping, Dong Xiaohua, Yang Zhangsheng, Li Zhongyu, Liu Quanzhong, Zhong Guangming

Abstract excerpt

Chlamydia trachomatis infection in the lower genital tract can ascend to and cause pathologies in the upper genital tract, potentially leading to severe complications, such as tubal infertility. However, chlamydial organisms depleted of plasmid or deficient in the plasmid-encoded Pgp3 are attenuated in ascending infection and no longer are able to induce the upper genital tract pathologies, indicating a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Bacterial
Share to Antimicrobial Cationic Peptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cathelicidins

Share to Chlamydia trachomatis

Share to HeLa Cells

Share to Host-Pathogen Interactions

Share to Plasmids

Share to Virulence Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 26416907
DOI: 10.1128/IAI.00746-15
PMCID: PMC4645396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chlamydial plasmid-encoded virulence factor Pgp3 neutralizes the antichlamydial activity of human cathelicidin LL-37.PMID 26416907Read ↗

Plasmid-mediated virulence in ChlamydiaSemantic proximity Read ↗

Structure of the Chlamydia trachomatis Immunodominant Antigen Pgp3Semantic proximity Read ↗

Plasmid-Encoded Pgp3 Is a Major Virulence Factor for Chlamydia muridarum To Induce Hydrosalpinx in MiceSemantic proximity Read ↗

The Genital Tract Virulence Factor pGP3 Is Essential for Chlamydia muridarum Colonization in the Gastrointestinal TractSemantic proximity Read ↗

Chlamydia trachomatis Plasmid-Encoded Pgp4 Is a Transcriptional Regulator of Virulence-Associated GenesSemantic proximity Read ↗

Plasmid-Encoded Pgp5 Is a Significant Contributor to Chlamydia muridarum Induction of HydrosalpinxSemantic proximity Read ↗

Unraveling the basic biology and clinical significance of the chlamydial plasmidSemantic proximity Read ↗

Infection of human organoids supports an intestinal niche for <i>Chlamydia trachomatis</i>Semantic proximity Read ↗

<i>Chlamydia</i> plasmid-encoded protein Pgp2 is a replication initiator with a unique β-hairpin necessary for iteron-binding and plasmid replicationSemantic proximity Read ↗

Gastrointestinal Chlamydia-Induced CD8 + T Cells Promote Chlamydial Pathogenicity in the Female Upper Genital TractSemantic proximity Read ↗

Chlamydia trachomatis Plasmid Protein pORF5 Up-Regulates ZFAS1 to Promote Host Cell Survival via MAPK/p38 PathwaySemantic proximity Read ↗

The Chlamydial Plasmid-Encoded Protein pgp3 Is Secreted into the Cytosol of<i>Chlamydia</i>-Infected CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.