Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gain-of-Function Research and the Relevance to Clinical Practice.

The Journal of infectious diseases - 1 May 2016

Kilianski Andy, Nuzzo Jennifer B, Modjarrad Kayvon

Abstract excerpt

The ongoing moratorium on gain-of-function (GOF) research with highly pathogenic avian influenza virus, severe acute respiratory syndrome coronavirus, and Middle East respiratory syndrome coronavirus has drawn attention to the current debate on these research practices and the potential benefits and risks they present. While much of the discussion has been steered by members of the microbiology and policy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Research
Share to Health Policy
Share to Influenza A virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Middle East Respiratory Syndrome Coronavirus

Share to Pandemics

Share to Research Design

Share to RNA Virus Infections

Share to Severe acute respiratory syndrome-related coronavirus

Source

Open in PubMed Open full text

Identifiers

PMID: 26416657
DOI: 10.1093/infdis/jiv473
PMCID: PMC7107371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gain-of-Function Research and the Relevance to Clinical Practice.PMID 26416657Read ↗

Gain-of-function experiments: time for a real debate.Semantic proximity Read ↗

Beyond gain of function: strengthening oversight of research with potential pandemic pathogensSemantic proximity Read ↗

The H5N1 Moratorium Controversy and DebateSemantic proximity Read ↗

Gain-of-Function Experiments on H7N9Semantic proximity Read ↗

The Reemergent 1977 H1N1 Strain and the Gain-of-Function DebateSemantic proximity Read ↗

Application of a Biologically Contained Reporter System To Study Gain-of-Function H5N1 Influenza A Viruses with Pandemic PotentialSemantic proximity Read ↗

MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studiesSemantic proximity Read ↗

Benefits and risks of influenza research: lessons learned.Semantic proximity Read ↗

Manipulation of the infectious bronchitis coronavirus genome for vaccine development and analysis of the accessory proteinsSemantic proximity Read ↗

Influenza reverse genetics: dissecting immunity and pathogenesisSemantic proximity Read ↗

A rat virus visits the clinic: translating basic discoveries into clinical medicine in the 21st century.Semantic proximity Read ↗

Vaccine-enhanced disease: case studies and ethical implications for research and public healthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.