Article
Simultaneous Estimation of Additive and Mutational Genetic Variance in an Outbred Population of Drosophila serrata.
Genetics - 1 Nov 2015
McGuigan Katrina, Aguirre J David, Blows Mark W
Abstract excerpt
How new mutations contribute to genetic variation is a key question in biology. Although the evolutionary fate of an allele is largely determined by its heterozygous effect, most estimates of mutational variance and mutational effects derive from highly inbred lines, where new mutations are present in homozygous form. In an attempt to overcome this limitation, middle-class neighborhood (MCN) experiments have been...
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