Article
Multiple Mutations Detected Preoperatively May Predict Aggressive Behavior of Papillary Thyroid Cancer and Guide Management--A Case Report.
Thyroid : official journal of the American Thyroid Association - 1 Dec 2015
Shrestha Rupendra T, Karunamurthy Arivarasan, Amin Khalid, Nikiforov Yuri E, Caramori M Luiza
Abstract excerpt
BACKGROUND: Multiple gene mutations in thyroid nodules are rare. The presence of several oncogenic mutations could be associated with aggressive biological behavior of tumors. PATIENT FINDINGS: A 60-year-old female presented to her physician after she felt a lump in her neck. On ultrasound, she was found to have a 1.4 cm × 0.8 cm × 1.3 cm nodule in the isthmus and a 0.5 cm × 0.6 cm × 0.6 cm nodule with irregular...
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