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Article

A five-miRNA signature with prognostic and predictive value for MGMT promoter-methylated glioblastoma patients.

Oncotarget - 6 Oct 2015

Cheng Wen, Ren Xiufang, Cai Jinquan, Zhang Chuanbao, Li Mingyang, Wang Kuanyu, Liu Yang, Han Sheng, Wu Anhua

Abstract excerpt

Although O(6)-methylguanine DNA methyltransferase (MGMT) promoter methylation status is an important marker for glioblastoma multiforme (GBM), there is considerable variability in the clinical outcome of patients with similar methylation profiles. The present study aimed to refine the prognostic and predictive value of MGMT promoter status in GBM by identifying a micro (mi)RNA risk signature. Data from The Cancer...

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Source

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Identifiers

PMID: 26320189
DOI: 10.18632/oncotarget.4978
PMCID: PMC4745726

Genes

MGMT

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Source receipt: pubmed, retrieved 7 Sept 2026.

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