Article
Target therapy of multiple myeloma by PTX-NPs and ABCG2 antibody in a mouse xenograft model.
Oncotarget - 29 Sept 2015
Yang Cuiping, Xiong Fei, Dou Jun, Xue Jun, Zhan Xi, Shi Fangfang, Li Miao, Wu Songyan, Luo Shouhua, Zhang Tianzhu, Zhang Yu, Ming Ji, Gu Ning
Abstract excerpt
Multiple myeloma (MM) remains to be an incurable disease. The purpose of this study was to evaluate the effect of ABCG2 monoclonal antibody (McAb) combined with paclitaxel (PTX) conjugated with Fe3O4 nanoparticles (NPs) on MM progressed from cancer stem cells (CSCs) in non-obese-diabetic/severe-c...
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