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Article

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix.

Proceedings of the National Academy of Sciences of the United States of America - 8 Sept 2015

Jennings Laura K, Storek Kelly M, Ledvina Hannah E, Coulon Charlène, Marmont Lindsey S, Sadovskaya Irina, Secor Patrick R, Tseng Boo Shan, Scian Michele, Filloux Alain, Wozniak Daniel J, Howell P Lynne, Parsek Matthew R

Abstract excerpt

Biofilm formation is a complex, ordered process. In the opportunistic pathogen Pseudomonas aeruginosa, Psl and Pel exopolysaccharides and extracellular DNA (eDNA) serve as structural components of the biofilm matrix. Despite intensive study, Pel's chemical structure and spatial localization within mature biofilms remain unknown. Using specialized carbohydrate chemical analyses, we unexpectedly found that Pel is a...

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Identifiers

PMID: 26311845
DOI: 10.1073/pnas.1503058112
PMCID: PMC4568648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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