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Article

The Role of a Novel TRMT1 Gene Mutation and Rare GRM1 Gene Defect in Intellectual Disability in Two Azeri Families.

PloS one - 1 Jan 2015

Davarniya Behzad, Hu Hao, Kahrizi Kimia, Musante Luciana, Fattahi Zohreh, Hosseini Masoumeh, Maqsoud Fariba, Farajollahi Reza, Wienker Thomas F, Ropers H Hilger, Najmabadi Hossein

Abstract excerpt

Cognitive impairment or intellectual disability (ID) is a widespread neurodevelopmental disorder characterized by low IQ (below 70). ID is genetically heterogeneous and is estimated to affect 1-3% of the world's population. In affected children from consanguineous families, autosomal recessive inheritance is common, and identifying the underlying genetic cause is an important issue in clinical genetics. In the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26308914
DOI: 10.1371/journal.pone.0129631
PMCID: PMC4550366

Genes

TRMT1
GRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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