Article
Genetic Determinants of Unruptured Intracranial Aneurysms in the General Population.
Stroke - 1 Oct 2015
Peymani Abbas, Adams Hieab H H, Cremers Lotte G M, Krestin Gabriel, Hofman Albert, van Duijn Cornelia M, Uitterlinden André G, van der Lugt Aad, Vernooij Meike W, Ikram M Arfan
Abstract excerpt
BACKGROUND AND PURPOSE: Genome-wide association studies have identified single-nucleotide polymorphisms (SNPs) for intracranial aneurysms in clinical samples. In addition, SNPs have been discovered for blood pressure, one of the strongest risk factors for intracranial aneurysms. We studied the role of these genetic variants on occurrence and size of unruptured intracranial aneurysms, discovered incidentally in a...
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