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Profiling microRNA expression in fracture nonunions

29 Jul 2015

Abstract excerpt

MicroRNAs (miRNAs ) are small non-coding RNAs that regulate gene expression. We hypothesised that the functions of certain miRNAs and changes to their patterns of expression may be crucial in the pathogenesis of nonunion. Healing fractures and atrophic nonunions produced by periosteal cauterisation were created in the femora of 94 rats, with 1:1 group allocation. At post-fracture days three, seven, ten, 14, 21...

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PMID: 26224835
DOI: 10.1302/0301-620x.97b8.34966

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