Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel SNP in 3' UTR of INS gene: A case report of neonatal diabetes mellitus.

Diabetes research and clinical practice - 1 Sept 2015

Bogari Neda M, Rayes Husni H, Mostafa Fakri, Abdel-Latif Azza M, Ramadan Abeer, Al-Allaf Faisal A, Taher Mohiuddin M, Fawzy Ahmed

Abstract excerpt

Neonatal diabetes mellitus (NDM) is a rare condition with a prevalence of 1 in 300,000 live births. We have found 3 known SNPs in 5'UTR and a novel SNP in 3' UTR in the INS gene. These SNPs were present in 9-month-old girl from Saudi Arabia and also present in the father and mother. The novel SNP we found is not present in 1000 Genome project or other databases. Further, the newly identified 3' UTR mutation in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus

Share to Infant

Share to Insulin

Share to Pedigree

Share to Polymorphism, Single Nucleotide

Share to Saudi Arabia

Source

Identifiers

PMID: 26212367
DOI: 10.1016/j.diabres.2015.06.002

Genes

INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel SNP in 3' UTR of INS gene: A case report of neonatal diabetes mellitus.PMID 26212367Read ↗

Permanent neonatal diabetes caused by creation of an ectopic splice site within the INS gene.Semantic proximity Read ↗

Continued lessons from the INS gene: an intronic mutation causing diabetes through a novel mechanism.Semantic proximity Read ↗

Identification of insulin gene variants in neonatal diabetes.Semantic proximity Read ↗

Case report: A 10-year prognosis of neonatal diabetes caused by a novel INS gene mutation.Semantic proximity Read ↗

Genetic variant profiling of neonatal diabetes mellitus in Iranian patients: Unveiling 58 distinct variants in 14 genes.Semantic proximity Read ↗

[Clinical and genetic analysis of an infant with permanent neonatal diabetes mellitus due to novel variant of insulin gene].Semantic proximity Read ↗

Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood.Semantic proximity Read ↗

Insulin gene mutations linked to permanent neonatal diabetes mellitus in Indian population.Semantic proximity Read ↗

One Novel 2.43Kb Deletion and One Single Nucleotide Mutation of the INSR Gene in a Chinese Neonate with Rabson-Mendenhall SyndromeSemantic proximity Read ↗

Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene.Semantic proximity Read ↗

Genotype and Phenotype Heterogeneity in Neonatal Diabetes: A Single Centre Experience in TurkeySemantic proximity Read ↗

Genetic characteristics, clinical spectrum, and incidence of neonatal diabetes in the Emirate of AbuDhabi, United Arab Emirates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.