Article
Emerging therapeutic options for Waldenström macroglobulinemia/lymphoplasmacytic lymphoma.
Expert review of anticancer therapy - 1 Jan 2015
Chakraborty Rajshekhar, Kapoor Prashant, Ansell Stephen M, Gertz Morie A
Abstract excerpt
Lymphoplasmacytic lymphoma is an indolent B-cell, non-Hodgkin lymphoma (NHL), the majority of which are characterized by production of a monoclonal immunoglobulin M (IgM) protein and are known as Waldenström macroglobulinemia. Identification of highly recurrent activating somatic mutation in MYD88 has improved our understanding of the pathogenesis of Waldenström macroglobulinemia and has therapeutic implications....
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