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Article

Prenatal Diagnosis of DNA Copy Number Variations by Genomic Single-Nucleotide Polymorphism Array in Fetuses with Congenital Heart Defects.

Fetal diagnosis and therapy - 1 Jan 2016

Tang Shaohua, Lv Jiaojiao, Chen Xiangnan, Bai Lili, Li Huanzheng, Chen Chong, Wang Ping, Xu Xueqin, Lu Jianxin

Abstract excerpt

OBJECTIVES: To evaluate the usefulness of single-nucleotide polymorphism (SNP) array for prenatal genetic diagnosis of congenital heart defect (CHD), we used this approach to detect clinically significant copy number variants (CNVs) in fetuses with CHDs. METHODS: A HumanCytoSNP-12 array was used to detect genomic samples obtained from 39 fetuses that exhibited cardiovascular abnormalities on ultrasound and had a...

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Share to DNA Copy Number Variations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Heart Defects, Congenital

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 26184588
DOI: 10.1159/000431320

Genes

BCOR
FLNA
RBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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