Article
A multidrug resistance plasmid contains the molecular switch for type VI secretion in Acinetobacter baumannii.
Proceedings of the National Academy of Sciences of the United States of America - 28 Jul 2015
Weber Brent S, Ly Pek Man, Irwin Joshua N, Pukatzki Stefan, Feldman Mario F
Abstract excerpt
Infections with Acinetobacter baumannii, one of the most troublesome and least studied multidrug-resistant superbugs, are increasing at alarming rates. A. baumannii encodes a type VI secretion system (T6SS), an antibacterial apparatus of Gram-negative bacteria used to kill competitors. Expression of the T6SS varies among different strains of A. baumannii, for which the regulatory mechanisms are unknown. Here, we...
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