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Article

Genome specialization and decay of the strangles pathogen, Streptococcus equi, is driven by persistent infection.

Genome research - 1 Sept 2015

Harris Simon R, Robinson Carl, Steward Karen F, Webb Katy S, Paillot Romain, Parkhill Julian, Holden Matthew T G, Waller Andrew S

Abstract excerpt

Strangles, the most frequently diagnosed infectious disease of horses worldwide, is caused by Streptococcus equi. Despite its prevalence, the global diversity and mechanisms underlying the evolution of S. equi as a host-restricted pathogen remain poorly understood. Here, we define the global population structure of this important pathogen and reveal a population replacement in the late 19th or early 20th Century....

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Identifiers

PMID: 26160165
DOI: 10.1101/gr.189803.115
PMCID: PMC4561494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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