Article
Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval.
European heart journal - 1 Oct 2015
Ghouse Jonas, Have Christian Theil, Weeke Peter, Bille Nielsen Jonas, Ahlberg Gustav, Balslev-Harder Marie, Appel Emil Vincent, Skaaby Tea, Olesen Søren-Peter, Grarup Niels, Linneberg Allan, Pedersen Oluf, Haunsø Stig, Hastrup Svendsen Jesper, Hansen Torben, Kanters Jørgen Kim, Salling Olesen Morten
Abstract excerpt
AIMS: We studied whether variants previously associated with congenital long QT syndrome (cLQTS) have an effect on the QTc interval in a Danish population sample. Furthermore, we assessed whether carriers of variants in cLQTS-associated genes are more prone to experience syncope compared with non-carriers and whether carriers have an increased mortality compared with non-carriers. METHODS AND RESULTS: All genetic...
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