Article
Dovitinib and erlotinib in patients with metastatic non-small cell lung cancer: A drug-drug interaction.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2015
Das Millie, Padda Sukhmani K, Frymoyer Adam, Zhou Lisa, Riess Jonathan W, Neal Joel W, Wakelee Heather A
Abstract excerpt
INTRODUCTION: Erlotinib is a FDA approved small molecule inhibitor of epidermal growth factor receptor and dovitinib is a novel small molecule inhibitor of fibroblast growth factor and vascular endothelial growth factor receptor. This phase 1 trial was conducted to characterize the safety and determine the maximum tolerated dose of erlotinib plus dovitinib in patients with previously treated metastatic non-small...
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