Article
APOE and LDLR Gene Polymorphisms and Dyslipidemia Tracking. Rio de Janeiro Study.
Arquivos brasileiros de cardiologia - 1 Jun 2015
Freitas Rossana Ghessa Andrade de, Campana Erika Maria Gonçalves, Pozzan Roberto, Brandão Andréa Araujo, Brandão Ayrton Pires, Magalhães Maria Eliane Campos, Silva Dayse Aparecida da
Abstract excerpt
BACKGROUND: Studies show an association between changes in apolipoprotein E (ApoE) and LDLR receptor with the occurrence of dyslipidemia. OBJECTIVES: To investigate the association between polymorphisms of the APOE (ε2, ε3, ε4) and LDLR (A370T) genes with the persistence of abnormal serum lipid levels in young individuals followed up for 17 years in the Rio de Janeiro Study. METHODS: The study included 56...
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