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Article

Variation in the X-linked EFHC2 gene is associated with social cognitive abilities in males.

PloS one - 1 Jan 2015

Startin Carla M, Fiorentini Chiara, de Haan Michelle, Skuse David H

Abstract excerpt

Females outperform males on many social cognitive tasks. X-linked genes may contribute to this sex difference. Males possess one X chromosome, while females possess two X chromosomes. Functional variations in X-linked genes are therefore likely to impact more on males than females. Previous studies of X-monosomic women with Turner syndrome suggest a genetic association with facial fear recognition abilities at...

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Identifiers

PMID: 26107779
DOI: 10.1371/journal.pone.0131604
PMCID: PMC4481314

Genes

EFHC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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