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Article

X Chromosomal effects on social cognitive processing and emotion regulation: A study with Klinefelter men (47,XXY).

Schizophrenia research - 1 Jun 2006

van Rijn Sophie, Swaab Hanna, Aleman André, Kahn René S

Abstract excerpt

Studying Klinefelter syndrome (47,XXY), a genetically defined disorder characterized by the presence of an additional X chromosome, can reveal insights into genotype-phenotype associations. Increased vulnerability to psychiatric disorders characterized by difficulties in social interactions, such as schizophrenia and autism, has been reported for this population. The reported social difficulties in 47,XXY men may...

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Identifiers

PMID: 16603340
DOI: 10.1016/j.schres.2006.02.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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