Clinical Role of Human Leukocyte Antigen in Health and Disease.

doi:10.1111/sji.12329

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Article

Clinical Role of Human Leukocyte Antigen in Health and Disease.

Scandinavian journal of immunology - 1 Oct 2015

Mosaad Y M

Abstract excerpt

Most of the genes in the major histocompatibility complex (MHC) region express high polymorphism that is fundamental for their function. The most important function of human leukocyte antigen (HLA) molecule is in the induction, regulation of immune responses and the selection of the T cell repertoire. A clinician's attention is normally drawn to a system only when it malfunctions. The HLA system is no exception...

Topics

Alleles
Antigen-Presenting Cells
Autoimmune Diseases
Dendritic Cells
Genes, MHC Class I
Genes, MHC Class II
HLA Antigens
Humans
T-Lymphocytes
Transplantation Immunology

Source

Open in PubMed

Identifiers

PMID: 26099424
DOI: 10.1111/sji.12329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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