Lectin‐based protein microarray analysis of differences in serum alpha‐2‐macroglobulin glycosylation between patients with colorectal cancer and persons without cancer

Abstract excerpt

Glycosylation is co- and posttranslational modifications affecting proteins. The glycopattern changes are associated with changes in biological function and are involved in many diseases including cancer. We present the lectin-based protein microarray method enabling determination of differences in protein glycosylation. The method involves isolation of targeted protein from samples by immunoprecipitation,...

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