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Article

In Vitro Spermatogenesis in Explanted Adult Mouse Testis Tissues.

PloS one - 1 Jan 2015

Sato Takuya, Katagiri Kumiko, Kojima Kazuaki, Komeya Mitsuru, Yao Masahiro, Ogawa Takehiko

Abstract excerpt

Research on in vitro spermatogenesis is important for elucidating the spermatogenic mechanism. We previously developed an organ culture method which can support spermatogenesis from spermatogonial stem cells up to sperm formation using immature mouse testis tissues. In this study, we examined whether it is also applicable to mature testis tissues of adult mice. We used two lines of transgenic mice, Acrosin-GFP...

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Source

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Identifiers

PMID: 26065832
DOI: 10.1371/journal.pone.0130171
PMCID: PMC4467084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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