Article
Molecular drug susceptibility testing in the Netherlands: performance of the MTBDRplus and MTBDRsl assays.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Jul 2015
Simons S O, van der Laan T, de Zwaan R, Kamst M, van Ingen J, Dekhuijzen P N R, Boeree M J, van Soolingen D
Abstract excerpt
BACKGROUND: The performance of molecular drug susceptibility testing in countries with a low prevalence of drug resistance, such as the Netherlands, has not been adequately studied. OBJECTIVE: To evaluate the diagnostic accuracy of the GenoType(®) MTBDRplus and MTBDRsl assays to detect resistance to first- and second-line anti-tuberculosis drugs in the context of a nationwide screening programme in the...
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