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Article

Chitotriosidase Expression during Monocyte-Derived Dendritic Cells Differentiation and Maturation.

Inflammation - 1 Dec 2015

Di Rosa Michelino, Tibullo Daniele, Cambria Daniela, Distefano Gisella, Saccone Salvatore, Di Raimondo Francesco, Malaguarnera Lucia

Abstract excerpt

The chitotriosidase (CHIT-1) is a glycosyl hydrolase (GH), which has been found highly expressed in activated macrophages and in different monocyte-derived cell lines such as Kupffer cells and osteoclasts, as well is differently produced in diverse stages of macrophage polarization (M1 and M2). Recent finding suggests that CHIT-1 plays a crucial role in innate and acquired immunity. Dendritic cells (DCs) are a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26026464
DOI: 10.1007/s10753-015-0190-5

Genes

CHIT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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