Article
Association of IL-6 and CRP gene polymorphisms with obesity and metabolic disorders in children and adolescents.
Anais da Academia Brasileira de Ciencias - 1 Jan 2000
Todendi Pâmela F, Klinger Elisa I, Ferreira Michele B, Reuter Cézane P, Burgos Miria S, Possuelo Lia G, Valim Andréia R M
Abstract excerpt
Activation of adipose tissue inflammation is associated with obesity caused by lipid accumulation in adipocytes. Through this activation, proinflammatory cytokines, such as Interleukin-6 (IL-6) and C-reactive protein (CRP) seem to influence metabolic disorders. The present study evaluated whether polymorphisms in the CRP (rs1205) and IL-6 (rs1800795, rs2069845) genes are associated with the development of...
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