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Article

Elevation of SIPL1 (SHARPIN) Increases Breast Cancer Risk

19 May 2015

Abstract excerpt

SIPL1 (Sharpin) or Sharpin plays a role in tumorigenesis. However, its involvement in breast cancer tumorigenesis remains largely unknown. To investigate this issue, we have systemically analyzed SIPL1 gene amplification and expression data available from Oncomine datasets, which were derived from 17 studies and contained approximately 20,000 genes, 3438 breast cancer cases, and 228 normal individuals. We found a...

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PMID: 25992689
DOI: 10.1371/journal.pone.0127546

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