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Article

Texture analysis of (125)I-A5B7 anti-CEA antibody SPECT differentiates metastatic colorectal cancer model phenotypes and anti-vascular therapy response.

British journal of cancer - 9 Jun 2015

Rajkumar V, Goh V, Siddique M, Robson M, Boxer G, Pedley R B, Cook G J R

Abstract excerpt

BACKGROUND: We aimed to test the ability of texture analysis to differentiate the spatial heterogeneity of (125)I-A5B7 anti-carcinoembryonic antigen antibody distribution by nano-single photon emission computed tomography (SPECT) in well-differentiated (SW1222) and poorly differentiated (LS174T) hepatic metastatic colorectal cancer models before and after combretastatin A1 di-phosphate anti-vascular therapy....

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Angiogenesis Inhibitors
Carcinoembryonic Antigen
Diphosphates
Heterografts
Iodine Radioisotopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Radiopharmaceuticals

Tomography, Emission-Computed, Single-Photon

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Identifiers

PMID: 25989271
DOI: 10.1038/bjc.2015.166
PMCID: PMC4580400

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