Article
Contribution of Clostridium difficile infection to the development of lower gastrointestinal adverse events during autologous stem cell transplantation.
Transplant infectious disease : an official journal of the Transplantation Society - 1 Aug 2015
Apewokin S, Goodwin J A, Lee J Y, Erickson S W, Sanathkumar N, Raj V R, Zhou D, McKelvey K D, Stephens O, Coleman E A
Abstract excerpt
BACKGROUND: Lower gastrointestinal (GI) adverse events (LGAE) are common afflictions of patients undergoing stem cell transplantation (SCT). Unfortunately, the pathophysiology remains poorly characterized. Emerging data suggest a prominent role of intestinal microbiota; however, contributions of pathogenic gut microbiota such as Clostridium difficile are not well defined. We performed a genome-wide association...
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