Article
Identification of a 6-cytokine prognostic signature in patients with primary glioblastoma harboring M2 microglia/macrophage phenotype relevance.
PloS one - 1 Jan 2015
Cai Jinquan, Zhang Wei, Yang Pei, Wang Yinyan, Li Mingyang, Zhang Chuanbao, Wang Zheng, Hu Huimin, Liu Yanwei, Li Qingbin, Wen Jinchong, Sun Bo, Wang Xiaofeng, Jiang Tao, Jiang Chuanlu
Abstract excerpt
BACKGROUND: Glioblastomas (GBM) are comprised of a heterogeneous population of tumor cells, immune cells, and extracellular matrix. Interactions among these different cell types and pro-/anti-inflammatory cytokines may promote tumor development and progression. AIMS: The objective of this study was to develop a cytokine-related gene signature to improve outcome prediction for patients with primary GBM. METHODS:...
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