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Article

HLA-B*38:55Q: a new alternatively expressed allele identified in a three-generation Italian family.

International journal of immunogenetics - 1 Aug 2015

Fusco C, Azzarone R, Penta R, Canossi A, Di Iulio B, Toriello M, Auriemma L, Pagano M, Poggi V, Papola F

Abstract excerpt

The new allelic variant HLA-B*38:55Q differs from the closest related B*38:01:01 by one nucleotide substitution at position 373 in exon 3 (TGC>CGC). This results in a difference of one amino acid at residue 101 of the HLA-B heavy chain, from a neutral-polar Cys to a basic-polar Arg, thus impairing disulphide bridge formation in the alpha-2 domain. This alteration of the secondary structure probably affects the...

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Source

Identifiers

PMID: 25976429
DOI: 10.1111/iji.12208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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