Article
Genetic determinants for gestational diabetes mellitus and related metabolic traits in Mexican women.
PloS one - 1 Jan 2015
Huerta-Chagoya Alicia, Vázquez-Cárdenas Paola, Moreno-Macías Hortensia, Tapia-Maruri Leonardo, Rodríguez-Guillén Rosario, López-Vite Erika, García-Escalante Guadalupe, Escobedo-Aguirre Fernando, Parra-Covarrubias Adalberto, Cordero-Brieño Roberto, Manzo-Carrillo Lizette, Zacarías-Castillo Rogelio, Vargas-García Carlos, Aguilar-Salinas Carlos, Tusié-Luna Teresa
Abstract excerpt
Epidemiological and physiological similarities among Gestational Diabetes Mellitus (GDM) and Type 2 Diabetes (T2D) suggest that both diseases, share a common genetic background. T2D risk variants have been associated to GDM susceptibility. However, the genetic architecture of GDM is not yet completely understood. We analyzed 176 SNPs for 115 loci previously associated to T2D, GDM and body mass index (BMI), as...
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