Article
Differential Genes Expression between Fertile and Infertile Spermatozoa Revealed by Transcriptome Analysis
14 May 2015
Abstract excerpt
BACKGROUND: It was believed earlier that spermatozoa have no traces of RNA because of loss of most of the cytoplasm. Recent studies have revealed the presence of about 3000 different kinds of mRNAs in ejaculated spermatozoa. However, the correlation of transcriptome profile with infertility remains obscure. METHODS: Total RNA from sperm (after exclusion of somatic cells) of 60 men consisting of individuals with...
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