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Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages

14 May 2015

Abstract excerpt

Human influenza viruses are responsible for annual epidemics and occasional pandemics that cause severe illness and mortality in all age groups worldwide. Matrix protein 2 (M2) of influenza A virus is a tetrameric type III membrane protein that functions as a proton-selective channel. The extracellular domain of M2 (M2e) is conserved in human and avian influenza A viruses and is being pursued as a component for a...

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PMID: 25973787
DOI: 10.1371/journal.pone.0126650

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