Article
Mipomersen and lomitapide: Two new drugs for the treatment of homozygous familial hypercholesterolemia.
Atherosclerosis. Supplements - 1 May 2015
Gouni-Berthold Ioanna, Berthold Heiner K
Abstract excerpt
Familial hypercholesterolemia (FH) is a disease associated with very high plasma concentrations of low-density lipoprotein cholesterol (LDL-C) and premature cardiovascular disease. It is difficult in these high risk patients, exposed lifelong to very high LDL-C, to reach target LDL-C concentrations, which require >50% LDL-C reduction, even when on maximally tolerated statin therapy and on apheresis if available....
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