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Article

LRP5 variants may contribute to ADPKD.

European journal of human genetics : EJHG - 1 Feb 2016

Cnossen Wybrich R, te Morsche René H M, Hoischen Alexander, Gilissen Christian, Venselaar Hanka, Mehdi Soufi, Bergmann Carsten, Losekoot Monique, Breuning Martijn H, Peters Dorien J M, Veltman Joris A, Drenth Joost P H

Abstract excerpt

Mutations in Polycystic Kidney Disease proteins (PKD1 or PKD2) are causative for autosomal dominant polycystic kidney disease (ADPKD). However, a small subset of ADPKD probands do not harbor a mutation in any of the known genes. Low density lipoprotein Receptor-related Protein 5 (LRP5) was recent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polycystic Kidney, Autosomal Dominant

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Source

Open in PubMed Open full text

Identifiers

PMID: 25920554
DOI: 10.1038/ejhg.2015.86
PMCID: PMC4717208

Genes

LRP5
PKD1
PKD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25920554-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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