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Article

Dysregulated flow‐mediated vasodilatation in the human placenta in fetal growth restriction

29 Apr 2015

Abstract excerpt

Key points A correlation was found between in vivo umbilical artery Doppler velocimetry and resistance to fetal‐side flow in the human ex vivo dually perfused placenta, highlighting that the fetoplacental vascular bed is a key site of resistance to umbilico‐placental flow in pregnancy. We discovered high resistance and poor flow‐mediated vasodilatory responses in placentas from pregnancies associated with fetal...

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PMID: 25920377
DOI: 10.1113/jp270495

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