Article
Major hereditary gastrointestinal cancer syndromes: a narrative review.
Journal of gastrointestinal and liver diseases : JGLD - 1 Jun 2017
Chintalacheruvu Lakshmi Manogna, Shaw Trudy, Buddam Avanija, Diab Osama, Kassim Thamer, Mukherjee Sandeep, Lynch Henry T
Abstract excerpt
Gastrointestinal cancer is one of the major causes of death worldwide. Hereditary gastrointestinal cancer syndromes constitute about 5-10% of all cancers. About 20-25% of undiagnosed cases have a possible hereditary component, which is not yet established. In the last few decades, the advance in genomics has led to the discovery of multiple cancer predisposition genes in gastrointestinal cancer. Physicians should...
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