Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Analysis of NOTCH2 in Patients with Primary Open-Angle Glaucoma.

Klinische Monatsblatter fur Augenheilkunde - 1 Apr 2015

Jakobsson C, Kheir V, Munier F L, Schorderet D F

Abstract excerpt

BACKGROUND AND PURPOSE: Transgenic mice overexpressing Notch2 in the uvea exhibit a hyperplastic ciliary body leading to increased IOP and glaucoma. The aim of this study was to investigate the possible presence of NOTCH2 variants in patients with primary open-angle glaucoma (POAG). METHODS: We screened DNA samples from 130 patients with POAG for NOTCH2 variants by denaturing high-performance liquid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Genetic Variation
Share to Glaucoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glaucoma, Open-Angle

Share to Mutation

Share to Polymorphism, Single Nucleotide

Share to Receptor, Notch2

Source

Identifiers

PMID: 25902091
DOI: 10.1055/s-0035-1545781

Genes

NOTCH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Analysis of NOTCH2 in Patients with Primary Open-Angle Glaucoma.PMID 25902091Read ↗

Major review: Molecular genetics of primary open-angle glaucoma.Semantic proximity Read ↗

Genome‐wide association studies in the hunt for genes causing primary open‐angle glaucoma: a reviewSemantic proximity Read ↗

Identification of TP53BP2 as a Novel Candidate Gene for Primary Open Angle Glaucoma by Whole Exome Sequencing in a Large Multiplex Family.Semantic proximity Read ↗

Genetic association between CDKN2B-AS1 polymorphisms and the susceptibility of primary open-angle glaucoma (POAG): a meta-analysis from 21,775 subjects.Semantic proximity Read ↗

Gene finding in primary open-angle glaucoma.Semantic proximity Read ↗

Polymorphism analysis of miR182 and CDKN2B genes in Greek patients with primary open angle glaucoma.Semantic proximity Read ↗

Investigation of CAV1/CAV2 rs4236601 and CDKN2B-AS1 rs2157719 in primary open-angle glaucoma patients from Brazil.Semantic proximity Read ↗

A Genome-Wide Scan for MicroRNA-Related Genetic Variants Associated With Primary Open-Angle Glaucoma.Semantic proximity Read ↗

Are we ready for genetic testing for primary open-angle glaucoma?Semantic proximity Read ↗

PAPPA2 c.392G>C Heterozygous Mutation Associates Primary Open-Angle Glaucoma in a Chinese Family.Semantic proximity Read ↗

The genetics of primary open angle glaucoma.Semantic proximity Read ↗

Meta-analysis of association between optineurin gene and primary open-angle glaucoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.